Palisade’s newspaper of record, The Palisade Tribune, is sold to the publishers of The Daily Sentinel in 2012. Two years later, in March 2014, the Tribune ceases to be printed. The community suffers from having no local news source. Palisade Historical Society negotiates for the archival newspapers in the building and then fundraises to get as many issues of the newspaper, beginning with the June 6, 1903 issue, digitized and available for research on the Colorado Historic Newspaper Collection website. Palisade has the only Medical marijuana outlet in Mesa County and voters approve retail marijuana stores in the November 2016 election. In addition to expanding into retail by the Medical Marijuana store, two more retail stores are authorized to sell marijuana by the Town Board.
Wineries continue to be a big attraction, though record peach crops continue to make Palisade a destination for tourists and locals. New crops grown in Palisade include lavender and hops.